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讲准字258号:基因工程的生物应用

发布时间:2018-09-18|浏览次数:

题目:基因工程的生物应用

主讲:王鹏飞

时间:2018年9月20日 14:30

地点:材料学院304报告厅

主办:材料学院


主讲简介:王鹏飞,上海交通大学医学院分子医学研究院研究员。研究专长:DNA纳米材料的组装与应用。设计并制备了复杂、可变形DNA纳米结构;DNA纳米材料在材料制备与肿瘤治疗方面的应用研究

 

主讲内容:DNA acts as the genetic information carrier for most living organisms on the planet. Nonetheless, DNA is not merely the secret of life. Attributing to its programmability derived from the specific Watson-Crick base pairing, DNA has long been utilized as a smart molecular ligand, for instance, to direct the interactions between materials, or to probe biological systems. My research grounds on the foundation of structural DNA nanotechnology, where DNA is used as basic building blocks that are programmed to self-assemble into prescribed structures with unprecedented fidelity that nearly impossible to achieve by other techniques. In the past years, I have been focusing on: (1) developing advanced self-assembly strategies to enrich the design toolbox of DNA self-assembly to allow people constructing structures with increased complexity; (2) Organizing non-biological (e.g. gold nanoparticles) and biological (e.g. siRNAs) functional materials onto DNA structures for applications in fabricating optical nanodevices and drug delivery. The overall theme of my future research is to design novel materials via engineering DNA and other functional materials for biomedical applications with primary interest in building molecular nanosystems enabling disease diagnosis and therapy.


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